The FDA is headed by the Director-General (DG), who is appointed by the President of the Philippines.
The Office of the Director General is assisted by two Deputy Director Generals (DDG), the DDG for Administration and Finance Office and the DDG for Field Regulatory Operations Office.
The FDA has four Centers, that are headed by the Center Directors. The Centers are named according to the major health product categories they regulate, as follows:
The following Offices, headed by Directors, support the operations of the four Centers, as follows:
As provided by law, the FDA maintains a Central Laboratory on top of the Laboratory Support Division of each Center.